W5LZ01_LEPOC protein (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

W5LZ01_LEPOC

Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (667 aa)

Predicted Functional Partners:

prkn

0.997

marchf5

0.986

LOC102691381

0.986

rhot2

0.975

rhot1

0.975

pink1

0.969

sqstm1

0.967

W5NCA6_LEPOC

0.962

tomm70

0.942

optn

0.935

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102691381	W5LZ01_LEPOC	ENSLOCP00000018524	ENSLOCP00000001358	Membrane-associated ring finger (C3HC4) 5, like.	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.986
LOC102691381	marchf5	ENSLOCP00000018524	ENSLOCP00000008610	Membrane-associated ring finger (C3HC4) 5, like.	Membrane associated ring-CH-type finger 5.	0.901
LOC102691381	prkn	ENSLOCP00000018524	ENSLOCP00000020388	Membrane-associated ring finger (C3HC4) 5, like.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.405
LOC102691381	rhot1	ENSLOCP00000018524	ENSLOCP00000016963	Membrane-associated ring finger (C3HC4) 5, like.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.911
LOC102691381	rhot2	ENSLOCP00000018524	ENSLOCP00000004100	Membrane-associated ring finger (C3HC4) 5, like.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.911
LOC102691381	tomm70	ENSLOCP00000018524	ENSLOCP00000013012	Membrane-associated ring finger (C3HC4) 5, like.	Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).	0.966
W5LZ01_LEPOC	LOC102691381	ENSLOCP00000001358	ENSLOCP00000018524	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Membrane-associated ring finger (C3HC4) 5, like.	0.986
W5LZ01_LEPOC	W5NCA6_LEPOC	ENSLOCP00000001358	ENSLOCP00000018265	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	0.962
W5LZ01_LEPOC	marchf5	ENSLOCP00000001358	ENSLOCP00000008610	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Membrane associated ring-CH-type finger 5.	0.986
W5LZ01_LEPOC	optn	ENSLOCP00000001358	ENSLOCP00000019349	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Optineurin.	0.935
W5LZ01_LEPOC	pink1	ENSLOCP00000001358	ENSLOCP00000002266	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	PTEN induced kinase 1.	0.969
W5LZ01_LEPOC	prkn	ENSLOCP00000001358	ENSLOCP00000020388	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.997
W5LZ01_LEPOC	rhot1	ENSLOCP00000001358	ENSLOCP00000016963	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.975
W5LZ01_LEPOC	rhot2	ENSLOCP00000001358	ENSLOCP00000004100	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.975
W5LZ01_LEPOC	sqstm1	ENSLOCP00000001358	ENSLOCP00000014082	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Sequestosome 1.	0.967
W5LZ01_LEPOC	tomm70	ENSLOCP00000001358	ENSLOCP00000013012	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).	0.942
W5NCA6_LEPOC	W5LZ01_LEPOC	ENSLOCP00000018265	ENSLOCP00000001358	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.962
W5NCA6_LEPOC	prkn	ENSLOCP00000018265	ENSLOCP00000020388	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.524
W5NCA6_LEPOC	rhot1	ENSLOCP00000018265	ENSLOCP00000016963	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.909
W5NCA6_LEPOC	rhot2	ENSLOCP00000018265	ENSLOCP00000004100	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.909