Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
W5LZ04_LEPOCDysferlin, limb girdle muscular dystrophy 2B (autosomal recessive). (2085 aa)    
Predicted Functional Partners:
anxa6
Annexin.
   
 0.728
TRIM50
Tripartite motif containing 50.
     
 0.669
anxa1
Annexin.
   
 0.638
W5NC51_LEPOC
Annexin.
   
 0.581
cav3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
   
 0.558
cav1
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
   
 0.558
pitrm1
Pitrilysin metallopeptidase 1.
      
 0.525
W5MHZ7_LEPOC
Anoctamin.
      
 0.521
anxa5
Annexin.
   
 0.516
W5NCR4_LEPOC
Annexin.
   
 0.516
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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