STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5LZ10_LEPOCRal GEF with PH domain and SH3 binding motif 1. (618 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
 0.927
magi3
Membrane associated guanylate kinase, WW and PDZ domain containing 3b.
    
 0.855
W5NC44_LEPOC
MAGI family member, X-linked b.
    
 0.855
lrguk
Leucine-rich repeats and guanylate kinase domain containing.
    
 0.776
grap
GRB2 related adaptor protein b.
   
 0.762
grap2
GRB2 related adaptor protein 2a.
   
 0.756
W5MKJ4_LEPOC
Protein tyrosine phosphatase non-receptor type 11b.
    
 0.751
W5MLN9_LEPOC
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.751
W5MLP2_LEPOC
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.751
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.702
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.