STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5LZ10_LEPOCRal GEF with PH domain and SH3 binding motif 1. (618 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.872
itsn2
Intersectin 2b.
    
 0.766
garnl3
GTPase activating Rap/RanGAP domain like 3.
      
 0.706
grap
GRB2 related adaptor protein b.
   
 0.663
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.651
itsn1
Intersectin 1 (SH3 domain protein).
    
 0.651
W5MJT7_LEPOC
V-crk avian sarcoma virus CT10 oncogene homolog.
    
 0.651
grap2
GRB2 related adaptor protein 2a.
    
 0.648
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.641
SHC3
SHC adaptor protein 3.
    
 0.641
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.