Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
W5LZ13_LEPOCB30.2/SPRY domain-containing protein. (338 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
  0.462
DDX41
DEAD-box helicase 41.
    
  0.457
pten
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
  0.452
LOC102693076
Transmembrane phosphatase with tensin homology.
    
  0.452
sqstm1
Sequestosome 1.
    
 0.449
ppl
Periplakin.
    
 0.442
LOC102688594
MACPF domain-containing protein.
  
     0.442
evpl
Envoplakin a.
    
 0.442
ube2n
Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.442
W5LWG1_LEPOC
Ig-like domain-containing protein.
  
     0.439
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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