| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| W5M3L3_LEPOC | W5MMZ7_LEPOC | ENSLOCP00000002971 | ENSLOCP00000009756 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Trans-2,3-enoyl-CoA reductase-like 2a. | 0.983 |
| W5M3L3_LEPOC | W5N8R7_LEPOC | ENSLOCP00000002971 | ENSLOCP00000017026 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.904 |
| W5M3L3_LEPOC | hacd1 | ENSLOCP00000002971 | ENSLOCP00000013438 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.902 |
| W5M3L3_LEPOC | hacd4 | ENSLOCP00000002971 | ENSLOCP00000013808 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.905 |
| W5M3L3_LEPOC | hsd17b12 | ENSLOCP00000002971 | ENSLOCP00000001376 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.974 |
| W5M3L3_LEPOC | tecr | ENSLOCP00000002971 | ENSLOCP00000012163 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Trans-2,3-enoyl-CoA reductase b. | 0.983 |
| W5MMZ7_LEPOC | W5M3L3_LEPOC | ENSLOCP00000009756 | ENSLOCP00000002971 | Trans-2,3-enoyl-CoA reductase-like 2a. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.983 |
| W5MMZ7_LEPOC | W5N8R7_LEPOC | ENSLOCP00000009756 | ENSLOCP00000017026 | Trans-2,3-enoyl-CoA reductase-like 2a. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.985 |
| W5MMZ7_LEPOC | elovl1 | ENSLOCP00000009756 | ENSLOCP00000004718 | Trans-2,3-enoyl-CoA reductase-like 2a. | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | 0.574 |
| W5MMZ7_LEPOC | hacd1 | ENSLOCP00000009756 | ENSLOCP00000013438 | Trans-2,3-enoyl-CoA reductase-like 2a. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.983 |
| W5MMZ7_LEPOC | hacd4 | ENSLOCP00000009756 | ENSLOCP00000013808 | Trans-2,3-enoyl-CoA reductase-like 2a. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.983 |
| W5MMZ7_LEPOC | hsd17b12 | ENSLOCP00000009756 | ENSLOCP00000001376 | Trans-2,3-enoyl-CoA reductase-like 2a. | Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.963 |
| W5MMZ7_LEPOC | tecr | ENSLOCP00000009756 | ENSLOCP00000012163 | Trans-2,3-enoyl-CoA reductase-like 2a. | Trans-2,3-enoyl-CoA reductase b. | 0.901 |
| W5N3Z7_LEPOC | W5N6Z3_LEPOC | ENSLOCP00000015356 | ENSLOCP00000016402 | Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family. | 0.984 |
| W5N3Z7_LEPOC | hsd17b12 | ENSLOCP00000015356 | ENSLOCP00000001376 | Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.962 |
| W5N3Z7_LEPOC | hsd17b7 | ENSLOCP00000015356 | ENSLOCP00000008624 | Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Hydroxysteroid (17-beta) dehydrogenase 7. | 0.934 |
| W5N6Z3_LEPOC | W5N3Z7_LEPOC | ENSLOCP00000016402 | ENSLOCP00000015356 | Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family. | Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.984 |
| W5N6Z3_LEPOC | hsd17b12 | ENSLOCP00000016402 | ENSLOCP00000001376 | Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family. | Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.968 |
| W5N6Z3_LEPOC | hsd17b7 | ENSLOCP00000016402 | ENSLOCP00000008624 | Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family. | Hydroxysteroid (17-beta) dehydrogenase 7. | 0.944 |
| W5N8R7_LEPOC | W5M3L3_LEPOC | ENSLOCP00000017026 | ENSLOCP00000002971 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.904 |