Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5LZ20_LEPOCMelanocyte-stimulating hormone receptor. (330 aa)    
Predicted Functional Partners:
pomc
Proopiomelanocortin b.
    
 0.999
W5MJZ4_LEPOC
Agouti signaling protein 1.
    
 0.998
mgrn1
Mahogunin, ring finger 1a.
    
 
 0.960
oca2
Oculocutaneous albinism II.
      
 0.864
tyrp1
Tyrosinase-related protein 1a.
    
 
 0.844
tyr
Tyrosinase.
    
 
 0.823
dct
Dopachrome tautomerase.
    
 
 0.820
W5M0U8_LEPOC
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.806
LOC102686598
Uncharacterized protein.
    
 0.757
edn3
Endothelin 3b.
    
 0.750
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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