Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lrp1bLow density lipoprotein receptor-related protein 1Ba. (4636 aa)    
Predicted Functional Partners:
lrpap1
Low density lipoprotein receptor-related protein associated protein 1.
    
 
 0.864
ldlrap1
Low density lipoprotein receptor adaptor protein 1a.
    
 0.789
W5MXT3_LEPOC
Amyloid beta (A4) precursor protein b.
    
 0.788
W5MQX5_LEPOC
DAB adaptor protein 1b.
    
 0.785
lrig1
Leucine-rich repeats and immunoglobulin-like domains 1.
    
 0.749
dkk1
Dickkopf WNT signaling pathway inhibitor 1b.
    
 0.739
wnt4
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.722
wnt1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.703
W5LXX5_LEPOC
Axin 1.
    
 0.700
axin2
Axin 2 (conductin, axil).
    
 0.700
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: medium (46%) [HD]