Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
sprSepiapterin reductase b. (272 aa)    
Predicted Functional Partners:
pah
Phenylalanine hydroxylase.
    
 0.993
W5N1Q0_LEPOC
6-pyruvoyltetrahydropterin synthase.
    
 0.992
qdpr
Zgc:171517.
   
 0.974
TPH1
Tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a.
    
 0.964
TPH2
Tryptophan hydroxylase 2.
    
 0.964
dhfr
Dihydrofolate reductase.
     
 0.957
th
Tyrosine hydroxylase.
    
 0.955
LOC102683960
Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.948
LOC102694946
Zgc:153031.
     
 0.923
LOC102683151
Aldo_ket_red domain-containing protein.
  
 0.909
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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