Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
W5LZ67_LEPOCHomeobox domain-containing protein. (290 aa)    
Predicted Functional Partners:
SMAD2
Mothers against decapentaplegic homolog.
    
 0.975
smad3
Mothers against decapentaplegic homolog.
    
 0.975
LOC102685535
TGFB-induced factor homeobox 1.
  
  
 
0.905
hdac1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.701
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.686
W5NKE7_LEPOC
Uncharacterized protein.
   
  
 0.624
nub1
Negative regulator of ubiquitin-like proteins 1.
   
   0.590
W5MIF3_LEPOC
Mothers against decapentaplegic homolog.
    
 0.577
W5N5D9_LEPOC
Mothers against decapentaplegic homolog.
    
 0.577
LOC102696492
Pre-B-cell leukemia homeobox 2.
    
 0.567
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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