Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cryaaCrystallin, alpha A; Belongs to the small heat shock protein (HSP20) family. (176 aa)    
Predicted Functional Partners:
cryab
Crystallin, alpha B, b; Belongs to the small heat shock protein (HSP20) family.
    
0.994
cryba1
Crystallin, beta A1a; Belongs to the beta/gamma-crystallin family.
   
 
 0.971
crybb2
Crystallin, beta B2; Belongs to the beta/gamma-crystallin family.
   
 
 0.962
BFSP1
Beaded filament structural protein 1; Belongs to the intermediate filament family.
      
 0.855
W5M936_LEPOC
Crystallin, gamma S1; Belongs to the beta/gamma-crystallin family.
   
 
 0.835
calcb
Calcitonin/calcitonin-related polypeptide, alpha.
    
   0.830
cryba2
Crystallin, beta A2b; Belongs to the beta/gamma-crystallin family.
   
  
 0.807
hspb1
Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family.
   
 0.751
W5M5W8_LEPOC
Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family.
   
 0.751
crybb1
Crystallin, beta B1; Belongs to the beta/gamma-crystallin family.
   
  
 0.749
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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