STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5LZA1_LEPOCDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (409 aa)    
Predicted Functional Partners:
mvk
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
 
 0.997
LOC102698835
Isopentenyl-diphosphate delta isomerase 1.
  
 
 0.980
W5MGX1_LEPOC
RUN and SH3 domain containing 1.
  
 0.973
hmgcr
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 
 0.959
ggps1
Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
  
 0.957
pdss1
Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.
  
 0.921
W5NIN3_LEPOC
Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family.
  
 0.921
lss
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 
 0.905
mthfr
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.903
W5MDX5_LEPOC
F-box protein 40, tandem duplicate 1.
  
 0.899
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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