STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pde6dRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] (155 aa)    
Predicted Functional Partners:
arl2
ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.
    
 0.981
W5MMK2_LEPOC
Retinitis pigmentosa GTPase regulator b.
    
 
 0.951
inpp5e
Inositol polyphosphate-5-phosphatase E.
    
 0.939
ARL3
ADP ribosylation factor like GTPase 3.
   
 0.924
LOC102683980
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
   
 0.924
LOC102695921
ADP ribosylation factor like GTPase 3, like 2; Belongs to the small GTPase superfamily. Arf family.
   
 0.883
gucy1a1
Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.880
gucy1a2
Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.873
LOC102684193
Guanylate cyclase.
    
 0.869
W5N7Q9_LEPOC
ANF_receptor domain-containing protein.
    
 0.869
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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