Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
W5LZN5_LEPOCProprotein convertase subtilisin/kexin type 1. (736 aa)    
Predicted Functional Partners:
pomc
Proopiomelanocortin b.
    
 0.829
LOC102694874
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.699
LOC102695073
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.699
W5MQF7_LEPOC
Barttin CLCNK-type chloride channel accessory beta subunit.
      
 0.626
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.620
pcsk9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
      
 0.619
W5NNQ3_LEPOC
Melanocortin 4 receptor.
   
  
 0.540
lgr4
Leucine-rich repeat containing G protein-coupled receptor 4.
    
 0.523
W5MI88_LEPOC
Uncharacterized protein.
    
 0.523
W5MNA3_LEPOC
Relaxin family peptide receptor 1.
    
 0.523
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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