STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5LZQ7_LEPOCL3MBTL histone methyl-lysine binding protein 1a. (784 aa)    
Predicted Functional Partners:
rnf2
Ring finger protein 2.
    
 0.739
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.683
yaf2
YY1 associated factor 2.
    
 0.610
rybp
RING1 and YY1 binding protein.
    
 0.610
cbx8
Chromobox homolog 8a (Pc class homolog, Drosophila).
    
 0.602
rbpj
Recombination signal binding protein for immunoglobulin kappa J region b.
   
 
 0.593
W5MXZ9_LEPOC
M-phase phosphoprotein 8.
    
 0.588
eed
Embryonic ectoderm development.
   
 0.586
cbx2
Chromobox homolog 2 (Drosophila Pc class).
    
 0.584
LOC102690826
Chromobox homolog 4 (Pc class homolog, Drosophila).
    
 0.582
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.