Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
casp1Uncharacterized protein; Belongs to the peptidase C14A family. (387 aa)    
Predicted Functional Partners:
NLRC4
NLR family CARD domain containing 4.
    
 0.995
LOC102686244
PYD and CARD domain containing.
   
 0.994
W5MBX3_LEPOC
PYD and CARD domain containing.
   
 0.975
W5N5W0_LEPOC
Uncharacterized protein.
   
 0.957
W5MXT6_LEPOC
Caspase 8; Belongs to the peptidase C14A family.
   
0.947
W5MFE7_LEPOC
Uncharacterized protein; Belongs to the peptidase C14A family.
  
  
 
0.904
W5MG35_LEPOC
Uncharacterized protein.
    
 0.875
nod1
Nucleotide-binding oligomerization domain containing 1.
   
 0.787
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.780
W5LZG1_LEPOC
NACHT domain-containing protein.
   
 0.747
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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