Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
bace2Beta-secretase 2; Belongs to the peptidase A1 family. (506 aa)    
Predicted Functional Partners:
W5MXT3_LEPOC
Amyloid beta (A4) precursor protein b.
    
 0.962
W5N1J9_LEPOC
Golgi-associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.884
aplp2
Amyloid beta (A4) precursor-like protein 2.
    
 0.846
W5M8N9_LEPOC
Amyloid beta (A4) precursor-like protein 1.
    
 0.734
W5N730_LEPOC
Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.
    
 0.733
W5MPY9_LEPOC
Seizure related 6 homolog (mouse)-like.
    
 
 0.652
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
     
 0.643
tmx1
Thioredoxin-related transmembrane protein 1.
    
  0.633
adam10
ADAM metallopeptidase domain 10b.
    
 
 0.588
lamp1
Lysosomal associated membrane protein 1a.
    
 
 0.572
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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