STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
snx8Sorting nexin 8b. (538 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
    
 0.979
msh3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
    
   0.946
nans
N-acetylneuraminic acid synthase a.
     
 0.873
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.860
snx5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.841
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.835
snx6
Sorting nexin 6.
   
 0.827
LOC102699080
Si:dkey-28n18.9.
   
 0.783
W5NFE5_LEPOC
Insulin-like growth factor 2 receptor.
    
 0.750
vps26b
VPS26, retromer complex component B.
    
 
 0.726
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.