Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5M000_LEPOCCathepsin 12; Belongs to the peptidase C1 family. (367 aa)    
Predicted Functional Partners:
bcl2l1
BCL2 like 1.
     
 0.900
bcl2
BCL2 apoptosis regulator b.
     
 0.900
W5NIN1_LEPOC
BH3 interacting domain death agonist.
     
  0.900
ctsd
Cathepsin D; Belongs to the peptidase A1 family.
   
 0.677
birc2
Baculoviral IAP repeat containing 2.
     
  0.650
LOC102696960
Uncharacterized protein.
     
  0.650
birc5
Baculoviral IAP repeat containing 5a.
     
  0.650
W5NBB2_LEPOC
X-linked inhibitor of apoptosis.
     
  0.650
tmprss2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
     
 0.620
chp1
Legumain.
   
 
 0.556
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.