Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
W5M013_LEPOCMicrotubule associated serine/threonine kinase 3a. (1323 aa)    
Predicted Functional Partners:
LOC102694326
Endosulfine alpha a; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.
    
 0.785
cabin1
Calcineurin binding protein 1.
      
 0.517
slc35d1
Solute carrier family 35 member D1a.
      
 0.503
nxnl1
Nucleoredoxin like 1.
      
 0.497
insl5
Insulin-like 5a.
      
 0.495
chek2
Checkpoint kinase 2.
   
    0.430
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 
 0.426
pten
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 
 0.426
W5MPI1_LEPOC
Cyclin A1; Belongs to the cyclin family.
   
 
 0.426
LOC102693076
Transmembrane phosphatase with tensin homology.
    
 
 0.426
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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