Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (729 aa)    
Predicted Functional Partners:
W5MRF2_LEPOC
GRB2-associated binding protein 1.
    
 0.992
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.988
pik3ca
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; Belongs to the PI3/PI4-kinase family.
    
 0.987
W5MJ15_LEPOC
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; Belongs to the PI3/PI4-kinase family.
    
 0.987
W5N7Y0_LEPOC
Zgc:158659; Belongs to the PI3/PI4-kinase family.
    
 0.987
cdc42
Cell division cycle 42.
    
 0.983
W5NLK8_LEPOC
Insulin receptor substrate 1.
    
 0.981
LOC102699081
Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.
    
 0.979
pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
 0.979
pdpk1
3-phosphoinositide dependent protein kinase 1a.
     
 0.974
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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