Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PDPRPyruvate dehydrogenase phosphatase regulatory subunit. (888 aa)    
Predicted Functional Partners:
gcsh
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
  
 0.978
gldc
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.964
pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.888
nudcd1
NudC domain containing 1.
    
   0.880
dlat
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.877
W5MBX6_LEPOC
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.873
W5MG14_LEPOC
Serine hydroxymethyltransferase 2 (mitochondrial).
  
 0.873
pdp2
Putative pyruvate dehydrogenase phosphatase isoenzyme 2.
  
 0.861
pdp1
Pyruvate dehyrogenase phosphatase catalytic subunit 1.
  
 0.861
LOC102689833
Si:ch211-15p9.2.
  
 0.861
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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