Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5M0E9_LEPOCUncharacterized protein. (351 aa)    
Predicted Functional Partners:
mep1a
Metalloendopeptidase.
    
 
 0.823
W5NIB3_LEPOC
Meprin A subunit.
    
 
 0.823
W5NFF8_LEPOC
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.798
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.696
W5M6C8_LEPOC
Family with sequence similarity 151 member A.
      
 0.678
RANBP2
RAN binding protein 2.
    
 0.656
fam216a
Uncharacterized protein.
      
 0.581
LOC102691579
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.542
tbc1d31
TBC1 domain family, member 31.
    
  0.538
eef1g
Eukaryotic translation elongation factor 1 gamma.
    
 0.521
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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