Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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W5M0G9_LEPOC5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (140 aa)    
Predicted Functional Partners:
LOC102689735
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.
 
 
 0.996
urad
Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase.
  
  
 0.986
rbp4
Retinol binding protein 4, plasma; Belongs to the calycin superfamily. Lipocalin family.
   
 0.955
allc
Allantoicase.
  
 
 0.788
W5N0L1_LEPOC
Albumin domain-containing protein.
   
  
 0.724
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
  
 
 0.668
W5MSU6_LEPOC
Squalene epoxidase a.
  
 
 0.652
LOC102690023
Zgc:103559.
 
   
 0.645
coq6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
  
 
  0.637
LOC102697922
FAD-binding PCMH-type domain-containing protein.
   
  
 0.599
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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