fam172a protein (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

fam172a

Family with sequence similarity 172 member A. (422 aa)

Predicted Functional Partners:

plac8l1

0.638

LOC107076412

0.601

LOC102696380

0.601

LOC102693418

0.601

LOC107076412-2

0.601

ago2

0.601

W5M0D4_LEPOC

0.600

cpped1

0.570

W5MDV2_LEPOC

0.525

W5N2L9_LEPOC

0.482

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102693418	LOC102696380	ENSLOCP00000000651	ENSLOCP00000000559	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Argonaute RISC component 1; Belongs to the argonaute family.	0.938
LOC102693418	ago2	ENSLOCP00000000651	ENSLOCP00000009441	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.937
LOC102693418	fam172a	ENSLOCP00000000651	ENSLOCP00000001899	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Family with sequence similarity 172 member A.	0.601
LOC102696380	LOC102693418	ENSLOCP00000000559	ENSLOCP00000000651	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.938
LOC102696380	ago2	ENSLOCP00000000559	ENSLOCP00000009441	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.900
LOC102696380	fam172a	ENSLOCP00000000559	ENSLOCP00000001899	Argonaute RISC component 1; Belongs to the argonaute family.	Family with sequence similarity 172 member A.	0.601
LOC107076412	fam172a	ENSLOCP00000000520	ENSLOCP00000001899	Piwi domain-containing protein.	Family with sequence similarity 172 member A.	0.601
LOC107076412-2	fam172a	ENSLOCP00000000686	ENSLOCP00000001899	Protein argonaute-1-like.	Family with sequence similarity 172 member A.	0.601
W5M0D4_LEPOC	fam172a	ENSLOCP00000001841	ENSLOCP00000001899	SMC5-SMC6 complex localization factor 1.	Family with sequence similarity 172 member A.	0.600
W5MDV2_LEPOC	fam172a	ENSLOCP00000006561	ENSLOCP00000001899	Arginine/serine-rich coiled-coil 2.	Family with sequence similarity 172 member A.	0.525
W5N2L9_LEPOC	fam172a	ENSLOCP00000014878	ENSLOCP00000001899	F-box protein 38.	Family with sequence similarity 172 member A.	0.482
ago2	LOC102693418	ENSLOCP00000009441	ENSLOCP00000000651	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.937
ago2	LOC102696380	ENSLOCP00000009441	ENSLOCP00000000559	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Argonaute RISC component 1; Belongs to the argonaute family.	0.900
ago2	fam172a	ENSLOCP00000009441	ENSLOCP00000001899	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Family with sequence similarity 172 member A.	0.601
cpped1	fam172a	ENSLOCP00000009083	ENSLOCP00000001899	Calcineurin-like phosphoesterase domain containing 1.	Family with sequence similarity 172 member A.	0.570
fam172a	LOC102693418	ENSLOCP00000001899	ENSLOCP00000000651	Family with sequence similarity 172 member A.	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.601
fam172a	LOC102696380	ENSLOCP00000001899	ENSLOCP00000000559	Family with sequence similarity 172 member A.	Argonaute RISC component 1; Belongs to the argonaute family.	0.601
fam172a	LOC107076412	ENSLOCP00000001899	ENSLOCP00000000520	Family with sequence similarity 172 member A.	Piwi domain-containing protein.	0.601
fam172a	LOC107076412-2	ENSLOCP00000001899	ENSLOCP00000000686	Family with sequence similarity 172 member A.	Protein argonaute-1-like.	0.601
fam172a	W5M0D4_LEPOC	ENSLOCP00000001899	ENSLOCP00000001841	Family with sequence similarity 172 member A.	SMC5-SMC6 complex localization factor 1.	0.600