Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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porNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (676 aa)    
Predicted Functional Partners:
W5MA66_LEPOC
Uncharacterized protein.
 
  
 
 0.929
LOC102686415
Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4.
 
  
 
 0.928
LOC102691147
Cytochrome P450, family 4, subfamily T, polypeptide 8; Belongs to the cytochrome P450 family.
 
  
 
 0.927
LOC102683375
Cytochrome P450, family 4, subfamily V, polypeptide 8; Belongs to the cytochrome P450 family.
 
  
 
 0.926
CYP4F8
Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family.
 
  
 
 0.897
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
   0.885
nat9
N-acetyltransferase 9 (GCN5-related, putative).
 
      0.881
W5MA21_LEPOC
Uncharacterized protein.
 
  
 
 0.870
hmox2
Heme oxygenase 2b.
    
 
 0.860
tbxas1
Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family.
 
  
 
 0.860
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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