Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nr2f1Nuclear receptor subfamily 2, group F, member 1a. (416 aa)    
Predicted Functional Partners:
fabp7
Fatty acid binding protein 7, brain, a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
    
 0.795
bola1
BolA family member 1; Belongs to the BolA/IbaG family.
      
 0.771
ano8
Anoctamin.
      
 0.754
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.668
hey2
Hes-related family bHLH transcription factor with YRPW motif 2.
    
 
 0.664
cops2
COP9 signalosome subunit 2.
    
   0.650
polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.618
W5M717_LEPOC
Nuclear receptor corepressor 1.
    
 0.588
W5MFZ2_LEPOC
Nuclear receptor corepressor 2.
    
 0.577
W5M7P2_LEPOC
Erb-b2 receptor tyrosine kinase 3b.
    
 0.546
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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