Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC102683281Sb:cb37. (1443 aa)    
Predicted Functional Partners:
cbx8
Chromobox homolog 8a (Pc class homolog, Drosophila).
    
 0.876
LOC102690826
Chromobox homolog 4 (Pc class homolog, Drosophila).
    
 0.873
rnf2
Ring finger protein 2.
    
 0.857
bmi1
Bmi1 polycomb ring finger oncogene 1b.
    
 0.776
W5N8B6_LEPOC
RING-type domain-containing protein.
    
 0.776
SCMH1
Scm polycomb group protein homolog 1.
    
 0.768
scml2
Scm polycomb group protein like 2.
    
 0.768
W5NFF8_LEPOC
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.724
cbx2
Chromobox homolog 2 (Drosophila Pc class).
    
 0.688
pcgf5
Polycomb group ring finger 5b.
    
 0.633
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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