Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5M0W0_LEPOCMitochondrial calcium uptake 2. (329 aa)    
Predicted Functional Partners:
micu1
Mitochondrial calcium uptake 1.
    
0.999
smdt1
Single-pass membrane protein with aspartate-rich tail 1b.
    
 0.999
mcu
Mitochondrial calcium uniporter.
    
 0.998
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
    
 0.996
micu3
Mitochondrial calcium uptake family, member 3b.
  
0.970
timm8a
Translocase of inner mitochondrial membrane 8 homolog A (yeast); Belongs to the small Tim family.
      
 0.885
ndufa8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.838
klhl22
Kelch-like family member 22.
    
   0.814
phb2
Prohibitin.
    
 0.813
LOC102698903
Cytochrome c oxidase assembly homolog 11 (yeast).
      
 0.809
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.