node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SUCLA2 | W5MMM6_LEPOC | ENSLOCP00000012787 | ENSLOCP00000009635 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | 0.630 |
SUCLA2 | acot11 | ENSLOCP00000012787 | ENSLOCP00000003926 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Acyl-CoA thioesterase 11a. | 0.806 |
SUCLA2 | aldh7a1 | ENSLOCP00000012787 | ENSLOCP00000010430 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. | 0.630 |
SUCLA2 | aldh9a1 | ENSLOCP00000012787 | ENSLOCP00000007306 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family. | 0.630 |
SUCLA2 | dlat | ENSLOCP00000012787 | ENSLOCP00000001728 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.973 |
SUCLA2 | etfa | ENSLOCP00000012787 | ENSLOCP00000018117 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Electron transfer flavoprotein subunit alpha. | 0.798 |
SUCLA2 | suclg1 | ENSLOCP00000012787 | ENSLOCP00000003035 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.999 |
SUCLA2 | suclg2 | ENSLOCP00000012787 | ENSLOCP00000012442 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.940 |
W5M2G8_LEPOC | W5MMM6_LEPOC | ENSLOCP00000002576 | ENSLOCP00000009635 | Malonyl-CoA decarboxylase. | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | 0.505 |
W5M2G8_LEPOC | acot11 | ENSLOCP00000002576 | ENSLOCP00000003926 | Malonyl-CoA decarboxylase. | Acyl-CoA thioesterase 11a. | 0.783 |
W5M2G8_LEPOC | aldh7a1 | ENSLOCP00000002576 | ENSLOCP00000010430 | Malonyl-CoA decarboxylase. | Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. | 0.505 |
W5M2G8_LEPOC | aldh9a1 | ENSLOCP00000002576 | ENSLOCP00000007306 | Malonyl-CoA decarboxylase. | Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family. | 0.505 |
W5M2G8_LEPOC | dlat | ENSLOCP00000002576 | ENSLOCP00000001728 | Malonyl-CoA decarboxylase. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.872 |
W5MMM6_LEPOC | SUCLA2 | ENSLOCP00000009635 | ENSLOCP00000012787 | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.630 |
W5MMM6_LEPOC | W5M2G8_LEPOC | ENSLOCP00000009635 | ENSLOCP00000002576 | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | Malonyl-CoA decarboxylase. | 0.505 |
W5MMM6_LEPOC | acot11 | ENSLOCP00000009635 | ENSLOCP00000003926 | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | Acyl-CoA thioesterase 11a. | 0.794 |
W5MMM6_LEPOC | aldh7a1 | ENSLOCP00000009635 | ENSLOCP00000010430 | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. | 0.899 |
W5MMM6_LEPOC | aldh9a1 | ENSLOCP00000009635 | ENSLOCP00000007306 | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family. | 0.873 |
W5MMM6_LEPOC | dlat | ENSLOCP00000009635 | ENSLOCP00000001728 | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.603 |
W5MMM6_LEPOC | suclg1 | ENSLOCP00000009635 | ENSLOCP00000003035 | Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.714 |