STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
notch1Notch receptor 1a. (2542 aa)    
Predicted Functional Partners:
rbpj
Recombination signal binding protein for immunoglobulin kappa J region b.
    
 0.996
maml1
Mastermind-like transcriptional coactivator 1.
    
 0.996
NCSTN
Nicastrin.
    
 0.987
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.977
dll1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.976
psen1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.975
W5NG78_LEPOC
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.975
W5MWB8_LEPOC
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.951
W5NBM6_LEPOC
Uncharacterized protein.
    
0.951
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.951
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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