STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
inpp5eInositol polyphosphate-5-phosphatase E. (592 aa)    
Predicted Functional Partners:
sacm1l
SAC1 like phosphatidylinositide phosphatase a.
 
  
 0.988
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 0.939
arl13b
ADP-ribosylation factor-like 13b.
     
 0.908
W5N090_LEPOC
Inositol polyphosphate-5-phosphatase F.
 
   
 0.895
W5MAJ9_LEPOC
Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a.
     
 0.879
pip5k1a
Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b.
     
 0.879
pip5k1b
Phosphatidylinositol-4-phosphate 5-kinase, type I, beta b.
     
 0.879
synj1
Synaptojanin 1.
    
0.876
pi4ka
Phosphatidylinositol 4-kinase, catalytic, alpha b; Belongs to the PI3/PI4-kinase family.
     
 0.871
W5MPG8_LEPOC
Phosphatidylinositol 4-kinase, catalytic, beta; Belongs to the PI3/PI4-kinase family.
     
 0.871
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.