STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5M7C3_LEPOCF-box protein 21. (638 aa)    
Predicted Functional Partners:
cul1
Cullin 1a; Belongs to the cullin family.
    
 0.939
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.866
cul3
Cullin 3a; Belongs to the cullin family.
    
 0.849
rasd1
RAS, dexamethasone-induced 1.
    
  0.717
ube2f
Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.
    
  0.708
rps27a
Ribosomal protein S27a.
   
  0.702
gatm
Glycine amidinotransferase (L-arginine:glycine amidinotransferase).
    
  0.697
grin1
Glutamate receptor, ionotropic, N-methyl D-aspartate 1b.
   
 
  0.695
nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
    
 0.683
uba3
Ubiquitin-like modifier activating enzyme 3.
    
 0.683
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.