W5M7D9_LEPOC protein (Lepisosteus oculatus) - STRING interaction network

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W5M7D9_LEPOC

SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (655 aa)

Predicted Functional Partners:

sumo1

0.999

W5NAP2_LEPOC

0.999

sumo3

0.979

sumo2

0.979

ube2i

0.971

LOC102683539

0.971

W5MZ98_LEPOC

0.971

kctd2

0.951

ube2f

0.925

atg3

0.878

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102683539	W5M7D9_LEPOC	ENSLOCP00000013698	ENSLOCP00000004297	UBIQUITIN_CONJUGAT_2 domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.971
LOC102683539	W5NAP2_LEPOC	ENSLOCP00000013698	ENSLOCP00000017701	UBIQUITIN_CONJUGAT_2 domain-containing protein.	SUMO1 activating enzyme subunit 1.	0.952
LOC102683539	sumo1	ENSLOCP00000013698	ENSLOCP00000012534	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Small ubiquitin-related modifier.	0.978
LOC102683539	sumo2	ENSLOCP00000013698	ENSLOCP00000016466	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Small ubiquitin-related modifier.	0.930
LOC102683539	sumo3	ENSLOCP00000013698	ENSLOCP00000011480	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Small ubiquitin-related modifier.	0.930
LOC102683539	ube2f	ENSLOCP00000013698	ENSLOCP00000005214	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	0.444
W5M7D9_LEPOC	LOC102683539	ENSLOCP00000004297	ENSLOCP00000013698	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.971
W5M7D9_LEPOC	W5MZ98_LEPOC	ENSLOCP00000004297	ENSLOCP00000013707	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.971
W5M7D9_LEPOC	W5NAP2_LEPOC	ENSLOCP00000004297	ENSLOCP00000017701	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO1 activating enzyme subunit 1.	0.999
W5M7D9_LEPOC	atg3	ENSLOCP00000004297	ENSLOCP00000001987	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Autophagy-related protein 3.	0.878
W5M7D9_LEPOC	kctd2	ENSLOCP00000004297	ENSLOCP00000013177	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Potassium channel tetramerization domain containing 2.	0.951
W5M7D9_LEPOC	sumo1	ENSLOCP00000004297	ENSLOCP00000012534	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Small ubiquitin-related modifier.	0.999
W5M7D9_LEPOC	sumo2	ENSLOCP00000004297	ENSLOCP00000016466	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Small ubiquitin-related modifier.	0.979
W5M7D9_LEPOC	sumo3	ENSLOCP00000004297	ENSLOCP00000011480	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Small ubiquitin-related modifier.	0.979
W5M7D9_LEPOC	ube2f	ENSLOCP00000004297	ENSLOCP00000005214	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	0.925
W5M7D9_LEPOC	ube2i	ENSLOCP00000004297	ENSLOCP00000004473	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	0.971
W5MZ98_LEPOC	W5M7D9_LEPOC	ENSLOCP00000013707	ENSLOCP00000004297	UBIQUITIN_CONJUGAT_2 domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.971
W5MZ98_LEPOC	W5NAP2_LEPOC	ENSLOCP00000013707	ENSLOCP00000017701	UBIQUITIN_CONJUGAT_2 domain-containing protein.	SUMO1 activating enzyme subunit 1.	0.952
W5MZ98_LEPOC	sumo1	ENSLOCP00000013707	ENSLOCP00000012534	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Small ubiquitin-related modifier.	0.978
W5MZ98_LEPOC	sumo2	ENSLOCP00000013707	ENSLOCP00000016466	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Small ubiquitin-related modifier.	0.930

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