STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102691967Solute carrier family 2 member 11b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (514 aa)    
Predicted Functional Partners:
CYB5R4
Cytochrome b5 reductase 4.
   
  0.761
W5NJ40_LEPOC
Epoxide hydrolase 2, cytoplasmic.
  
 
 0.573
gapdhs
Glyceraldehyde-3-phosphate dehydrogenase.
   
 0.546
gapdh
Glyceraldehyde-3-phosphate dehydrogenase.
   
 0.546
tk1
Thymidine kinase.
     
 0.525
cstf3
Cleavage stimulation factor, 3' pre-RNA, subunit 3.
  
 
 0.517
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.512
LOC102699166
Solute carrier family 22 member 7a.
  
 
 0.512
tyms
Thymidylate synthetase.
  
 
  0.506
rab14
RAB14, member RAS oncogene family.
     
 0.492
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.