STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102697715Zgc:171592; Belongs to the peptidase S1 family. (265 aa)    
Predicted Functional Partners:
mst1r
Macrophage stimulating 1 receptor b.
    
  0.751
met
MET proto-oncogene, receptor tyrosine kinase.
    
  0.751
W5LXM6_LEPOC
Peptidase S1 domain-containing protein.
  
0.749
W5M9F9_LEPOC
Serine protease 1; Belongs to the peptidase S1 family.
  
0.743
LOC102688622
Si:dkey-33m11.7; Belongs to the peptidase S1 family.
  
0.735
W5MXT3_LEPOC
Amyloid beta (A4) precursor protein b.
 
  
 0.638
LOC107076243
Uncharacterized protein.
 
 
 0.633
W5NFF8_LEPOC
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
  
0.596
magi3
Membrane associated guanylate kinase, WW and PDZ domain containing 3b.
     
 0.593
tfpi
Tissue factor pathway inhibitor.
    
 0.590
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.