atp8a2 protein (Lepisosteus oculatus) - STRING interaction network

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Predicted Interactions

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atp8a2

Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1221 aa)

Predicted Functional Partners:

LOC102686030

0.836

tmem30a

0.836

W5MTQ7_LEPOC

0.787

W5N0B4_LEPOC

0.787

LOC102685598

0.782

sec63

0.642

lyst

0.582

mkln1

0.580

clvs2

0.574

LOC102685941

0.562

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102685598	atp8a2	ENSLOCP00000005416	ENSLOCP00000004911	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.782
LOC102685941	atp8a2	ENSLOCP00000018333	ENSLOCP00000004911	Zgc:66447.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.562
LOC102685941	clvs2	ENSLOCP00000018333	ENSLOCP00000021347	Zgc:66447.	Clavesin 2.	0.633
LOC102685941	lyst	ENSLOCP00000018333	ENSLOCP00000019463	Zgc:66447.	Lysosomal trafficking regulator.	0.505
LOC102685941	mkln1	ENSLOCP00000018333	ENSLOCP00000019256	Zgc:66447.	Muskelin 1, intracellular mediator containing kelch motifs.	0.651
LOC102685941	sec63	ENSLOCP00000018333	ENSLOCP00000020500	Zgc:66447.	SEC63 homolog, protein translocation regulator.	0.556
LOC102686030	atp8a2	ENSLOCP00000011485	ENSLOCP00000004911	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.836
W5MTQ7_LEPOC	W5N0B4_LEPOC	ENSLOCP00000011766	ENSLOCP00000014073	NME/NM23 family member 8; Belongs to the NDK family.	Uncharacterized protein; Belongs to the NDK family.	0.919
W5MTQ7_LEPOC	atp8a2	ENSLOCP00000011766	ENSLOCP00000004911	NME/NM23 family member 8; Belongs to the NDK family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.787
W5N0B4_LEPOC	W5MTQ7_LEPOC	ENSLOCP00000014073	ENSLOCP00000011766	Uncharacterized protein; Belongs to the NDK family.	NME/NM23 family member 8; Belongs to the NDK family.	0.919
W5N0B4_LEPOC	atp8a2	ENSLOCP00000014073	ENSLOCP00000004911	Uncharacterized protein; Belongs to the NDK family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.787
atp8a2	LOC102685598	ENSLOCP00000004911	ENSLOCP00000005416	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.782
atp8a2	LOC102685941	ENSLOCP00000004911	ENSLOCP00000018333	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Zgc:66447.	0.562
atp8a2	LOC102686030	ENSLOCP00000004911	ENSLOCP00000011485	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.836
atp8a2	W5MTQ7_LEPOC	ENSLOCP00000004911	ENSLOCP00000011766	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	NME/NM23 family member 8; Belongs to the NDK family.	0.787
atp8a2	W5N0B4_LEPOC	ENSLOCP00000004911	ENSLOCP00000014073	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Uncharacterized protein; Belongs to the NDK family.	0.787
atp8a2	clvs2	ENSLOCP00000004911	ENSLOCP00000021347	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Clavesin 2.	0.574
atp8a2	lyst	ENSLOCP00000004911	ENSLOCP00000019463	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Lysosomal trafficking regulator.	0.582
atp8a2	mkln1	ENSLOCP00000004911	ENSLOCP00000019256	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Muskelin 1, intracellular mediator containing kelch motifs.	0.580
atp8a2	sec63	ENSLOCP00000004911	ENSLOCP00000020500	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	SEC63 homolog, protein translocation regulator.	0.642

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Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.766

expected number of edges:

20

PPI enrichment p-value:

0.0814

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016052

Carbohydrate catabolic process

5 of 28

1.91

2.44

5.04e-06

GO:0019310

Inositol catabolic process

2 of 2

2.66

1.07

0.0112

GO:0005975

Carbohydrate metabolic process

6 of 186

1.17

1.04

0.00071

GO:0005996

Monosaccharide metabolic process

3 of 35

1.6

0.94

0.0112

GO:0044282

Small molecule catabolic process

4 of 121

1.18

0.76

0.0121

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1519

0.48

0.36

0.0076

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:963

Mixed, incl. Pentose phosphate pathway, and Glycolytic process

5 of 53

1.64

1.75

7.94e-05

CL:2352

Mixed, incl. AMP metabolic process, and GMP biosynthesis

3 of 11

2.1

1.47

0.0015

CL:1045

Mostly uncharacterized, incl. Carbohydrate kinase PfkB, and UxaA/GarD, SAF domain

3 of 12

2.06

1.46

0.0015

CL:2356

GMP biosynthesis, and De novo AMP biosynthetic process

2 of 5

2.26

0.92

0.0196

CL:974

Glycolysis, and Glyceraldehyde-3-phosphate dehydrogenase, type I

2 of 7

2.12

0.87

0.0240

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00030

Pentose phosphate pathway

5 of 39

1.77

2.4

2.24e-06

map01200

Carbon metabolism

5 of 292

0.9

0.61

0.0099

map01120

Microbial metabolism in diverse environments

6 of 540

0.71

0.47

0.0141

map01100

Metabolic pathways

11 of 1791

0.45

0.38

0.00073

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

9 of 1044

0.6

0.43

0.0071

GOCC:0005622

Intracellular

10 of 1615

0.45

0.33

0.0122

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