STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK2Cyclin dependent kinase 2. (252 aa)    
Predicted Functional Partners:
W5MPI1_LEPOC
Cyclin A1; Belongs to the cyclin family.
   
 0.987
ccna2
Cyclin A2; Belongs to the cyclin family.
 
 
 0.985
ccne1
Cyclin E1; Belongs to the cyclin family.
   
 0.977
ccne2
Cyclin E2; Belongs to the cyclin family.
   
 0.975
rb1
Retinoblastoma 1.
   
 0.975
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.971
cdkn1a
Cyclin-dependent kinase inhibitor 1A.
   
 0.968
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.964
LOC102682951
Cyclin-dependent kinase inhibitor 1Cb.
   
 0.953
W5MTM3_LEPOC
CDC23 (cell division cycle 23, yeast, homolog).
    
 0.952
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.