STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)    
Predicted Functional Partners:
pik3r3
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.958
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.956
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 0.955
mras
Muscle RAS oncogene homolog.
   
 0.951
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 0.944
rras2
RAS related 2.
   
 0.942
W5MJ15_LEPOC
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; Belongs to the PI3/PI4-kinase family.
  
  
 
0.932
W5NLK8_LEPOC
Insulin receptor substrate 1.
   
 0.912
irs4
Insulin receptor substrate 4a.
   
 0.912
W5NMP3_LEPOC
Insulin receptor substrate 2b.
   
 0.912
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.