STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRD3Bromodomain containing 3. (743 aa)    
Predicted Functional Partners:
LOC102699233
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.861
taf7l
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
    
 
 0.860
W5LYD5_LEPOC
E2F transcription factor 1.
    
 
 0.793
W5M4H6_LEPOC
DNA methyltransferase 1 associated protein 1.
    
 
 0.735
nsd3
Nuclear receptor binding SET domain protein 3.
    
 
 0.717
jmjd6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
    
 
 0.716
taf1
Transcription initiation factor TFIID subunit.
    
 
0.707
cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase).
    
 
 0.705
crbn
Cereblon.
    
 
 0.653
yeats4
YEATS domain containing 4.
    
 
 0.649
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.