STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
piezo1Piezo-type mechanosensitive ion channel component. (2541 aa)    
Predicted Functional Partners:
chek2
Checkpoint kinase 2.
    
 0.954
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
   
 0.930
mcm4
DNA helicase; Belongs to the MCM family.
   
 0.900
timeless
Timeless circadian clock.
    
 
 0.868
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
    
 0.847
W5N2L8_LEPOC
WD repeat and HMG-box DNA binding protein 1.
   
 
 0.846
mcm2
DNA helicase; Belongs to the MCM family.
   
 0.796
mcm9
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
   
 0.796
W5MPK4_LEPOC
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.786
W5N8X8_LEPOC
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.786
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.