VSIG2 protein (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

VSIG2

V-set and immunoglobulin domain containing 2. (294 aa)

Predicted Functional Partners:

W5NNN1_LEPOC

0.886

cldn2

0.792

cldn11

0.790

cldn18

0.783

cog8

0.661

cog3

0.651

CLDN8

0.632

CLDN8-2

0.632

tsta3

0.580

COG5

0.568

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN8	VSIG2	ENSLOCP00000011118	ENSLOCP00000006152	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	V-set and immunoglobulin domain containing 2.	0.632
CLDN8	W5NNN1_LEPOC	ENSLOCP00000011118	ENSLOCP00000022240	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.789
CLDN8	cldn11	ENSLOCP00000011118	ENSLOCP00000008809	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.790
CLDN8	cldn18	ENSLOCP00000011118	ENSLOCP00000007488	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.797
CLDN8	cldn2	ENSLOCP00000011118	ENSLOCP00000021591	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.788
CLDN8-2	VSIG2	ENSLOCP00000022152	ENSLOCP00000006152	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	V-set and immunoglobulin domain containing 2.	0.632
CLDN8-2	W5NNN1_LEPOC	ENSLOCP00000022152	ENSLOCP00000022240	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.789
CLDN8-2	cldn11	ENSLOCP00000022152	ENSLOCP00000008809	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.790
CLDN8-2	cldn18	ENSLOCP00000022152	ENSLOCP00000007488	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.797
CLDN8-2	cldn2	ENSLOCP00000022152	ENSLOCP00000021591	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.788
COG5	VSIG2	ENSLOCP00000019474	ENSLOCP00000006152	Component of oligomeric golgi complex 5.	V-set and immunoglobulin domain containing 2.	0.568
COG5	cog3	ENSLOCP00000019474	ENSLOCP00000006566	Component of oligomeric golgi complex 5.	Component of oligomeric golgi complex 3.	0.999
COG5	cog8	ENSLOCP00000019474	ENSLOCP00000001587	Component of oligomeric golgi complex 5.	Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.	0.999
VSIG2	CLDN8	ENSLOCP00000006152	ENSLOCP00000011118	V-set and immunoglobulin domain containing 2.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.632
VSIG2	CLDN8-2	ENSLOCP00000006152	ENSLOCP00000022152	V-set and immunoglobulin domain containing 2.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.632
VSIG2	COG5	ENSLOCP00000006152	ENSLOCP00000019474	V-set and immunoglobulin domain containing 2.	Component of oligomeric golgi complex 5.	0.568
VSIG2	W5NNN1_LEPOC	ENSLOCP00000006152	ENSLOCP00000022240	V-set and immunoglobulin domain containing 2.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.886
VSIG2	cldn11	ENSLOCP00000006152	ENSLOCP00000008809	V-set and immunoglobulin domain containing 2.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.790
VSIG2	cldn18	ENSLOCP00000006152	ENSLOCP00000007488	V-set and immunoglobulin domain containing 2.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.783
VSIG2	cldn2	ENSLOCP00000006152	ENSLOCP00000021591	V-set and immunoglobulin domain containing 2.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.792