ube2v2 protein (Lepisosteus oculatus) - STRING interaction network

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ube2v2

Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)

Predicted Functional Partners:

ube2n

0.999

birc6

0.992

rps27a

0.985

hltf

0.983

uba52

0.978

RNF8

0.941

ube2k

0.938

W5MVF4_LEPOC

0.917

W5NK42_LEPOC

0.915

W5M7P1_LEPOC

0.914

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RNF8	W5M7P1_LEPOC	ENSLOCP00000020254	ENSLOCP00000004399	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Ubiquitin-conjugating enzyme E2W (putative).	0.557
RNF8	W5MVF4_LEPOC	ENSLOCP00000020254	ENSLOCP00000012363	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Uncharacterized protein.	0.900
RNF8	birc6	ENSLOCP00000020254	ENSLOCP00000020602	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Baculoviral IAP repeat containing 6.	0.686
RNF8	rps27a	ENSLOCP00000020254	ENSLOCP00000019146	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Ribosomal protein S27a.	0.963
RNF8	uba52	ENSLOCP00000020254	ENSLOCP00000002515	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.954
RNF8	ube2k	ENSLOCP00000020254	ENSLOCP00000015998	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.596
RNF8	ube2n	ENSLOCP00000020254	ENSLOCP00000018805	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.	0.987
RNF8	ube2v2	ENSLOCP00000020254	ENSLOCP00000007265	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Ubiquitin-conjugating enzyme E2 variant 2.	0.941
W5M7P1_LEPOC	RNF8	ENSLOCP00000004399	ENSLOCP00000020254	Ubiquitin-conjugating enzyme E2W (putative).	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.557
W5M7P1_LEPOC	W5MVF4_LEPOC	ENSLOCP00000004399	ENSLOCP00000012363	Ubiquitin-conjugating enzyme E2W (putative).	Uncharacterized protein.	0.821
W5M7P1_LEPOC	W5NK42_LEPOC	ENSLOCP00000004399	ENSLOCP00000021001	Ubiquitin-conjugating enzyme E2W (putative).	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.446
W5M7P1_LEPOC	birc6	ENSLOCP00000004399	ENSLOCP00000020602	Ubiquitin-conjugating enzyme E2W (putative).	Baculoviral IAP repeat containing 6.	0.781
W5M7P1_LEPOC	rps27a	ENSLOCP00000004399	ENSLOCP00000019146	Ubiquitin-conjugating enzyme E2W (putative).	Ribosomal protein S27a.	0.817
W5M7P1_LEPOC	uba52	ENSLOCP00000004399	ENSLOCP00000002515	Ubiquitin-conjugating enzyme E2W (putative).	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.827
W5M7P1_LEPOC	ube2k	ENSLOCP00000004399	ENSLOCP00000015998	Ubiquitin-conjugating enzyme E2W (putative).	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.750
W5M7P1_LEPOC	ube2n	ENSLOCP00000004399	ENSLOCP00000018805	Ubiquitin-conjugating enzyme E2W (putative).	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.	0.806
W5M7P1_LEPOC	ube2v2	ENSLOCP00000004399	ENSLOCP00000007265	Ubiquitin-conjugating enzyme E2W (putative).	Ubiquitin-conjugating enzyme E2 variant 2.	0.914
W5MVF4_LEPOC	RNF8	ENSLOCP00000012363	ENSLOCP00000020254	Uncharacterized protein.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.900
W5MVF4_LEPOC	W5M7P1_LEPOC	ENSLOCP00000012363	ENSLOCP00000004399	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2W (putative).	0.821
W5MVF4_LEPOC	W5NK42_LEPOC	ENSLOCP00000012363	ENSLOCP00000021001	Uncharacterized protein.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.677