W5MHU9_LEPOC protein (Lepisosteus oculatus) - STRING interaction network

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Score

W5MHU9_LEPOC

SEA domain-containing protein. (281 aa)

Predicted Functional Partners:

itsn2

0.980

mysm1

0.898

dctn2

0.784

actr2

0.777

W5NB73_LEPOC

0.776

arpc3

0.775

actr8

0.772

W5MLC2_LEPOC

0.768

dctn4

0.766

dctn5

0.765

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W5MHU9_LEPOC	W5MLC2_LEPOC	ENSLOCP00000007958	ENSLOCP00000009181	SEA domain-containing protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.768
W5MHU9_LEPOC	W5NB73_LEPOC	ENSLOCP00000007958	ENSLOCP00000017882	SEA domain-containing protein.	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.	0.776
W5MHU9_LEPOC	actr2	ENSLOCP00000007958	ENSLOCP00000019749	SEA domain-containing protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.777
W5MHU9_LEPOC	actr8	ENSLOCP00000007958	ENSLOCP00000017444	SEA domain-containing protein.	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	0.772
W5MHU9_LEPOC	arpc3	ENSLOCP00000007958	ENSLOCP00000008757	SEA domain-containing protein.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.775
W5MHU9_LEPOC	dctn2	ENSLOCP00000007958	ENSLOCP00000007043	SEA domain-containing protein.	Dynactin 2 (p50).	0.784
W5MHU9_LEPOC	dctn4	ENSLOCP00000007958	ENSLOCP00000014533	SEA domain-containing protein.	Dynactin 4.	0.766
W5MHU9_LEPOC	dctn5	ENSLOCP00000007958	ENSLOCP00000006796	SEA domain-containing protein.	Dynactin 5.	0.765
W5MHU9_LEPOC	itsn2	ENSLOCP00000007958	ENSLOCP00000001168	SEA domain-containing protein.	Intersectin 2b.	0.980
W5MHU9_LEPOC	mysm1	ENSLOCP00000007958	ENSLOCP00000010813	SEA domain-containing protein.	Myb-like, SWIRM and MPN domains 1.	0.898
W5MLC2_LEPOC	W5MHU9_LEPOC	ENSLOCP00000009181	ENSLOCP00000007958	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	SEA domain-containing protein.	0.768
W5MLC2_LEPOC	W5NB73_LEPOC	ENSLOCP00000009181	ENSLOCP00000017882	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.	0.645
W5MLC2_LEPOC	actr2	ENSLOCP00000009181	ENSLOCP00000019749	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.822
W5MLC2_LEPOC	actr8	ENSLOCP00000009181	ENSLOCP00000017444	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	0.746
W5MLC2_LEPOC	arpc3	ENSLOCP00000009181	ENSLOCP00000008757	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.833
W5MLC2_LEPOC	dctn2	ENSLOCP00000009181	ENSLOCP00000007043	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Dynactin 2 (p50).	0.984
W5MLC2_LEPOC	dctn4	ENSLOCP00000009181	ENSLOCP00000014533	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Dynactin 4.	0.982
W5MLC2_LEPOC	dctn5	ENSLOCP00000009181	ENSLOCP00000006796	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Dynactin 5.	0.976
W5NB73_LEPOC	W5MHU9_LEPOC	ENSLOCP00000017882	ENSLOCP00000007958	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.	SEA domain-containing protein.	0.776
W5NB73_LEPOC	W5MLC2_LEPOC	ENSLOCP00000017882	ENSLOCP00000009181	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.645