STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sergefSecretion regulating guanine nucleotide exchange factor. (396 aa)    
Predicted Functional Partners:
dph3
DPH-type MB domain-containing protein.
    
 
 0.979
RANBP2
RAN binding protein 2.
   
 0.726
W5M227_LEPOC
Usher syndrome 1C.
    
 
 0.720
KCNJ11
Potassium inwardly-rectifying channel, subfamily J, member 11.
      
 0.696
znf536
Zinc finger protein 536.
    
 0.689
ZFC3H1
Zinc finger C3H1-type containing.
      
 0.648
W5MSZ0_LEPOC
Zinc finger, AN1-type domain 4.
    
 0.635
W5MI16_LEPOC
Anoctamin.
      
 0.632
ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    
 
 0.623
TSPAN8
Tetraspanin.
      
 0.580
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.