STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cachd1Cache domain containing 1. (1292 aa)    
Predicted Functional Partners:
cacng1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
    
 0.936
cacnb4
Calcium channel, voltage-dependent, beta 4a subunit.
    
 0.883
W5MKU2_LEPOC
Calcium channel, voltage-dependent, beta 3a.
    
 0.883
cacnb2
Calcium voltage-gated channel auxiliary subunit beta 2.
    
 0.883
cacnb1
Calcium channel, voltage-dependent, beta 1 subunit.
    
 0.883
W5M0J9_LEPOC
Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.
   
 0.786
CACNA1A
Calcium voltage-gated channel subunit alpha1 A.
   
 0.786
cacna1e
Calcium channel, voltage-dependent, R type, alpha 1E subunit a.
   
 0.786
LOC107076501
Ion_trans domain-containing protein.
   
 0.786
CATSPER3
Cation channel sperm associated 3.
   
 0.785
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.