node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SUCLA2 | W5MIG5_LEPOC | ENSLOCP00000012787 | ENSLOCP00000008174 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | SET domain containing 4. | 0.768 |
SUCLA2 | W5N4K7_LEPOC | ENSLOCP00000012787 | ENSLOCP00000015566 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | 0.554 |
SUCLA2 | cs | ENSLOCP00000012787 | ENSLOCP00000005579 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Citrate synthase; Belongs to the citrate synthase family. | 0.991 |
SUCLA2 | dlst | ENSLOCP00000012787 | ENSLOCP00000013103 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Dihydrolipoamide S-succinyltransferase. | 0.987 |
SUCLA2 | mdh2 | ENSLOCP00000012787 | ENSLOCP00000001970 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Malate dehydrogenase. | 0.875 |
SUCLA2 | suclg1 | ENSLOCP00000012787 | ENSLOCP00000003035 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.999 |
SUCLA2 | suclg2 | ENSLOCP00000012787 | ENSLOCP00000012442 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.940 |
W5MIG5_LEPOC | SUCLA2 | ENSLOCP00000008174 | ENSLOCP00000012787 | SET domain containing 4. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.768 |
W5MIG5_LEPOC | W5MPB9_LEPOC | ENSLOCP00000008174 | ENSLOCP00000010228 | SET domain containing 4. | MINDY lysine 48 deubiquitinase 1. | 0.684 |
W5MIG5_LEPOC | W5N4K7_LEPOC | ENSLOCP00000008174 | ENSLOCP00000015566 | SET domain containing 4. | ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | 0.760 |
W5MIG5_LEPOC | W5N840_LEPOC | ENSLOCP00000008174 | ENSLOCP00000016799 | SET domain containing 4. | MINDY lysine 48 deubiquitinase 2. | 0.684 |
W5MIG5_LEPOC | cs | ENSLOCP00000008174 | ENSLOCP00000005579 | SET domain containing 4. | Citrate synthase; Belongs to the citrate synthase family. | 0.707 |
W5MIG5_LEPOC | dlst | ENSLOCP00000008174 | ENSLOCP00000013103 | SET domain containing 4. | Dihydrolipoamide S-succinyltransferase. | 0.702 |
W5MIG5_LEPOC | mdh2 | ENSLOCP00000008174 | ENSLOCP00000001970 | SET domain containing 4. | Malate dehydrogenase. | 0.701 |
W5MIG5_LEPOC | mmaa | ENSLOCP00000008174 | ENSLOCP00000010794 | SET domain containing 4. | Metabolism of cobalamin associated A. | 0.684 |
W5MIG5_LEPOC | suclg1 | ENSLOCP00000008174 | ENSLOCP00000003035 | SET domain containing 4. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.725 |
W5MIG5_LEPOC | suclg2 | ENSLOCP00000008174 | ENSLOCP00000012442 | SET domain containing 4. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.840 |
W5MPB9_LEPOC | W5MIG5_LEPOC | ENSLOCP00000010228 | ENSLOCP00000008174 | MINDY lysine 48 deubiquitinase 1. | SET domain containing 4. | 0.684 |
W5N4K7_LEPOC | SUCLA2 | ENSLOCP00000015566 | ENSLOCP00000012787 | ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.554 |
W5N4K7_LEPOC | W5MIG5_LEPOC | ENSLOCP00000015566 | ENSLOCP00000008174 | ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | SET domain containing 4. | 0.760 |