STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpped1Calcineurin-like phosphoesterase domain containing 1. (312 aa)    
Predicted Functional Partners:
nudt12
Nudix (nucleoside diphosphate linked moiety X)-type motif 12.
   
 0.899
W5NJ40_LEPOC
Epoxide hydrolase 2, cytoplasmic.
    
 0.878
pudp
Pseudouridine 5'-phosphatase.
  
 
 0.840
minpp1
Multiple inositol-polyphosphate phosphatase 1b; Belongs to the histidine acid phosphatase family.
     
 0.823
rfk
Riboflavin kinase.
    
 0.822
acp1
LMWPc domain-containing protein.
    
 0.815
W5MJF1_LEPOC
Flavin adenine dinucleotide synthetase 1.
    
  0.790
kmt5b
Lysine methyltransferase 5B.
     
 0.704
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
    
  0.649
icmt
Protein-S-isoprenylcysteine O-methyltransferase.
    
  0.646
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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