STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5MLP5_LEPOCLysine (K)-specific methyltransferase 2D. (5142 aa)    
Predicted Functional Partners:
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.985
rbbp5
Retinoblastoma binding protein 5.
    
 0.984
wdr5
WD repeat domain 5.
    
 0.957
kdm6a
Lysine (K)-specific demethylase 6A.
   
 0.915
LOC102699233
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.913
W5M045_LEPOC
Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b.
    
  0.870
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
    
  0.870
prkaa2
Non-specific serine/threonine protein kinase.
   
  0.859
ttc33
Non-specific serine/threonine protein kinase.
   
  0.859
men1
Multiple endocrine neoplasia I.
    
 0.851
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.