STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nr3c2Nuclear receptor subfamily 3, group C, member 2. (987 aa)    
Predicted Functional Partners:
nr3c1
Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor).
    
0.877
pgr
Progesterone receptor.
     
0.773
W5MKE7_LEPOC
Prostaglandin E synthase 3b (cytosolic).
   
  0.759
LOC102697673
Peptidylprolyl isomerase.
    
 0.753
fkbp4
Peptidylprolyl isomerase.
    
 0.753
ncoa3
Nuclear receptor coactivator.
    
 0.730
ncoa2
Nuclear receptor coactivator.
    
 0.730
ncoa1
Nuclear receptor coactivator 1.
    
 0.730
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.723
W5M717_LEPOC
Nuclear receptor corepressor 1.
    
 0.716
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.