STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (668 aa)    
Predicted Functional Partners:
pi4ka
Phosphatidylinositol 4-kinase, catalytic, alpha b; Belongs to the PI3/PI4-kinase family.
    
 0.947
W5MHK8_LEPOC
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.
    
 0.911
LDLR
Low density lipoprotein receptor.
    
 0.911
vldlr
Very low density lipoprotein receptor.
    
 0.911
W5MM02_LEPOC
Inositol polyphosphate phosphatase-like 1a.
    
 0.897
LOC102682643
Inositol polyphosphate phosphatase-like 1b.
    
 0.897
W5MPG8_LEPOC
Phosphatidylinositol 4-kinase, catalytic, beta; Belongs to the PI3/PI4-kinase family.
    
 0.884
synj1
Synaptojanin 1.
    
 0.872
W5M8B5_LEPOC
Phosphoinositide kinase, FYVE finger containing.
    
 0.862
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.848
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.